Arsenal are not only hoping to win a first European trophy since 1994, but know their hopes of qualifying for next year's Champions League depend on winning the Europa League in the French city of Lyon next month.
Manchester United's Rasmus Hojlund and Alejandro Garnacho ended goal droughts and Bruno Fernandes scored again to earn a 3-0 win at struggling Leicester City.
The match was called off a day before the fixture after Spurs manager Antonio Conte said eight players and five members of staff had tested positive for COVID-19.
After scoring twice in Chelsea's 4-1 win over Arsenal in the Europa League final, Eden Hazard said it was the moment to call time on his magnificent career with the London club to seek new challenges.
Liverpool overcame an early scare and came from a goal down to claim a 3-1 win at Austria's LASK Linz.
Roma have taken just four points from their last five league matches, and were eliminated from the Coppa Italia last week in a 1-0 defeat to rivals Lazio.
IMAGES from Europa League matches played on Thursday.
An early penalty by Alexis Mac Allister and a Darwin Nunez brace helped Liverpool to thrash Sparta Prague 5-1.
Tottenham have not won any silverware since they beat Chelsea in the 2008 League Cup final.
The decision followed talks with Greek authorities, UEFA said.
A summary of Sunday's action in the Premier League.
Antoine Griezmann and Samuel Lino scored in each half to give Atletico Madrid a 2-0 win over Lazio on Wednesday that secured them top spot in Champions League Group E, the first time since 2016 that they had reached the knockouts as group winners.
Manchester United should focus on winning the Europa League this season, which would bring the club a trophy they have never won and secure qualification for next season's Champions League, former manager Alex Ferguson has said.
Holders Manchester City will take on RB Leipzig, Red Star Belgrade and Young Boys in Group G.
Liverpool moved one win away from sealing the Premier League title as substitute Trent Alexander-Arnold secured a 1-0 victory at Leicester City
The Millennium Stadium in Cardiff will host the 2017 Champions League final, UEFA general secretary Gianni Infantino said on Tuesday. The Friends Arena in Stockholm will be the venue for the 2017 Europa League final.
A round-up of Saturday's action in the UEFA Nations League group stage matches.
Reach fifth round for first time in 10 years
'We created loads of chances in our seven (Premier League) games but we have to step up.'
Images from Europa League matches played across Europe on Thursday.
Ruud van Nistelrooy will take over on an interim basis.
Arsenal's Arteta wary of old foe Villa
Ajax keeper Remko Pasveer made five saves and scored on his own attempt to help the hosts win the shootout as Dutch international Brian Brobbey missed two penalties.
Mohamed Salah's early penalty in the return match on Thursday gave Liverpool a 1-0 victory in Italy but Klopp's side went out 3-1 on aggregate.
Manchester United needed an extra-time winner from Marcus Rashford to defeat Anderlecht 2-1 at Old Trafford on Thursday and move into the last four of the Europa League with a 3-2 aggregate victory.
United captain Jesse Lingard fired them ahead in the 10th minute with a fizzing low shot from 20 metres before Dmitri Shomko and a Di'Shon Bernard own goal turned the match on its head shortly after half-time.
Barcelona have reached the semis only once since winning the Champions League in 2014-15.
With Crystal Palace dangerously close to being relegated, manager Patrick Vieira was sacked after 20 months in charge.
Images from UEFA Champions League matches played on Wednesday.
Rubin Kazan, Udinese, Bruges and AZ Alkmaar qualified for the Europa league knock-out stages on Thursday and will go into the draw for the round of 32 with big guns Manchester United and Manchester City after their Champions League elimination.
Liverpool resumed their march to a second Premier League title on Sunday with a 2-1 victory over West Ham United.
Sevilla conjured up a dazzling comeback to clinch a record third successive Europa League title on Wednesday, flooring Liverpool with a 3-1 victory that showed why the Spanish side have become masters of Europe's second-tier competition.
Shakhtar dominated possession as expected but were toothless up front and Inter opened the scoring with their first chance after 19 minutes.
Al-Nassr have appointed Stefano Pioli as manager to replace Luis Castro, the Saudi Pro League club said on Wednesday.
West Ham United, reduced to 10 men after defender James Tomkins was sent off in the first half, won 5-3 in a penalty shootout against Maltese Cup winners Birkirkara to scrape into the Europa League third qualifying round on Thursday.
Kiev's Olympic stadium will host the final of the 2018 Champions League, the first final of Europe's top club competition to be held in Ukraine, UEFA said on Thursday.
Jarrod Bowen converted a last-gasp penalty to lift West Ham United to a 2-1 Premier League victory over Manchester United in a fluctuating clash between two struggling sides on Sunday.
Bayer Leverkusen won their first trophy in 31 years with five matches left in the season, snapping Bayern Munich's 11-year stranglehold on the Bundesliga.
The win left Chelsea in 11th position, a point and one place behind Newcastle but with a game in hand.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
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